Please use this identifier to cite or link to this item:
Title: The phylodynamics of the rabies virus in the Russian Federation
Authors: Deviatkin, Andrei A 
Lukashev, Alexander N 
Poleshchuk, Elena M 
Dedkov, Vladimir G 
Tkachev, Sergey E 
Sidorov, Gennadiy N 
Karganova, Galina G 
Galkina, Irina V 
Shchelkanov, Mikhail Yu 
Shipulin, German A 
Issue Date: 22-Feb-2017
Publisher: Public Library of Science
Source: Deviatkin AA, Lukashev AN, Poleshchuk EM, Dedkov VG, Tkachev SE, Sidorov GN, et al. (2017) The phylodynam ics of the rabies virus in the Russian Federation. PLoS ONE 12(2): e0171855.
Journal: PloS one 
Abstract: Near complete rabies virus N gene sequences (1,110 nt) were determined for 82 isolates obtained from different regions of Russia between 2008 and 2016. These sequences were analyzed together with 108 representative GenBank sequences from 1977-2016 using the Bayesian coalescent approach. The timing of the major evolutionary events was estimated. Most of the isolates represented the steppe rabies virus group C, which was found over a vast geographic region from Central Russia to Mongolia and split into three groups (C0-C2) with discrete geographic prevalence. A single strain of the steppe rabies virus lineage was isolated in the far eastern part of Russia (Primorsky Krai), likely as a result of a recent anthropogenic introduction. For the first time the polar rabies virus group A2, previously reported in Alaska, was described in the northern part of European Russia and at the Franz Josef Land. Phylogenetic analysis suggested that all currently circulating rabies virus groups in the Russian Federation were introduced within the few last centuries, with most of the groups spreading in the 20th century. The dating of evolutionary events was highly concordant with the historical epidemiological data.
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0171855
Appears in Collections:Cтатьи в журналах/Journal articles

Files in This Item:
File Description SizeFormat 
journal.pone.0171855.pdf1.53 MBAdobe PDFView/Open
Show full item record


checked on Nov 8, 2018

Page view(s) 50

checked on Nov 14, 2018

Download(s) 50

checked on Nov 14, 2018

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.