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Title: Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia
Authors: Chernyaeva, Ekaterina
Rotkevich, Mikhail
Krasheninnikova, Ksenia
Yurchenko, Andrey
Solovieva, Natalia
Zhuravlev, Viacheslav
Yablonsky, Piotr
O'Brien, Stephen J
Vyazovaya, Anna A. 
Mokrousov, Igor V. 
Keywords: Mycobacterium tuberculosis;Russia;WGS;antimicrobial resistance;bacteria;bacterial virulence;drug resistance;genetic markers;genome determinants;pathogenicity;phylogeny;tuberculosis and other mycobacteria;tuberculous spondylitis;whole-genome sequencing
Issue Date: Mar-2018
Publisher: Centers for Disease Control and Prevention
Journal: Emerging Infectious Disease 
Abstract: Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.
ISSN: 1080-6040
DOI: 10.3201/eid2403.170151
Appears in Collections:Journal articles

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