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Title: Next-Generation Sequencing of Mycobacterium tuberculosis
Authors: Chernyaeva, Ekaterina
Sinkov, Viacheslav
Zhuravlev, Viacheslav
Mokrousov, Igor V. 
Vyazovaya, Anna A. 
Narvskaya, Olga V. 
Keywords: Mycobacterium tuberculosis;bacteria;next-generation sequencing;spoligotyping;tuberculosis and other mycobacteria;whole-genome sequencing
Issue Date: Jun-2016
Publisher: Centers for Disease Control and Prevention
Journal: Emerging Infectious Disease 
Abstract: Next-generation sequencing (NGS) technology is becoming more affordable and is increasingly being widely used for high-resolution molecular epidemiology of tuberculosis. Using an example of the emerging multidrug-resistant strain of Mycobacterium tuberculosis, we showed the value of informed understanding when in silico prediction from NGS data achieved with available bioinformatics tools is placed within the context of the existing genotyping framework.
ISSN: 1080-6040
DOI: 10.3201/eid2206.152051
Appears in Collections:Journal articles

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