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Title: Genetic diversity of the Mycobacterium tuberculosis Beijing family in Brazil and Mozambique and relation with infectivity and induction of necrosis in THP-1 cells
Authors: Gomes, Lia Lima
Vasconcellos, Sidra Ezidrio Gonçalves
Gomes, Harrison Magdinier
Elias, Atina Ribeiro
da Silva Rocha, Adalgiza
Ribeiro, Simone C M
Panunto, Alessandra Costa
Ferrazoli, Lucilaine
da Silva Telles, Maria Alice
Ivens de, Araujo Marelo Emanuel
Kritski, Afranio Lineu
Manicheva, Olga A
Lasunskaia, Elena
Suffys, Philip Noel
Mokrousov, Igor V. 
Keywords: Beijing;Genotypes;Mozambique and Brazil;Mycobacterium tuberculosis;Virulence
Issue Date: Jun-2015
Publisher: Elsevier
Journal: Tuberculosis 
Abstract: The success of the Mycobacterium tuberculosis Beijing (MtbB) lineage in different geographical regions has been attributed to high transmission, increased virulence, drug resistance and rapid adaptation to the host. In some countries of secondary MtbB dispersion like South Africa and Peru, rising prevalence of the Beijing strains is registered. However, in neighboring countries to affected regions such as Mozambique and Brazil, respectively, the prevalence of these strains is still low and this could be due to biological particularities of the circulating MtbB strains and/or differentiated host susceptibility.
ISSN: 1472-9792
DOI: 10.1016/
Appears in Collections:Journal articles

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